Katherine A Fitzgerald Selected Research

Carrier Proteins (Binding Protein)

11/2023	Cellular nucleic acid-binding protein restricts SARS-CoV-2 by regulating interferon and disrupting RNA-protein condensates.
1/2021	Cellular nucleic acid-binding protein is essential for type I interferon-mediated immunity to RNA virus infection.
10/2013	Cyclic-di-GMP and cyclic-di-AMP activate the NLRP3 inflammasome.

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Katherine A Fitzgerald Research Topics

Disease

62	Infections 02/2024 - 01/2004
47	Bites and Stings (Sting) 04/2024 - 11/2010
44	Inflammation (Inflammations) 01/2024 - 08/2008
17	Virus Diseases (Viral Diseases) 01/2018 - 05/2003
12	Autoimmune Diseases (Autoimmune Disease) 10/2022 - 07/2006
11	Malaria 01/2024 - 08/2011
11	Melanoma (Melanoma, Malignant) 01/2021 - 10/2005
9	Neoplasms (Cancer) 09/2023 - 11/2012
4	COVID-19 11/2023 - 01/2021
4	Tuberculosis (Tuberculoses) 01/2022 - 07/2009
4	Fibrosis (Cirrhosis) 01/2019 - 05/2010
4	Porcine Reproductive and Respiratory Syndrome (PRRS) 03/2016 - 09/2009
4	Arthritis (Polyarthritis) 02/2016 - 02/2013
3	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 02/2024 - 09/2010
3	Colitis 01/2023 - 09/2010
3	Systemic Lupus Erythematosus (Libman-Sacks Disease) 10/2022 - 09/2013
3	Familial Mediterranean Fever (Periodic Disease) 01/2020 - 02/2013
3	Sepsis (Septicemia) 01/2019 - 07/2006
3	Atherosclerosis 08/2013 - 07/2006
2	Interstitial Lung Diseases (Interstitial Lung Disease) 04/2024 - 01/2022
2	Ulcerative Colitis 02/2024 - 01/2022
2	RNA Virus Infections 01/2021 - 01/2019
2	Bacterial Infections (Bacterial Infection) 01/2019 - 01/2017
2	Myocardial Infarction 12/2017 - 07/2013
2	Splenomegaly 02/2016 - 07/2015
2	Mitochondrial Diseases (Mitochondrial Disease) 09/2015 - 03/2012
2	Alcoholic Liver Diseases (Alcoholic Liver Disease) 08/2015 - 10/2013
2	Fever (Fevers) 01/2014 - 02/2013
2	Alzheimer Disease (Alzheimer's Disease) 08/2013 - 08/2008
2	Candidiasis (Moniliasis) 12/2011 - 05/2009
1	Toxoplasmosis 02/2024

Drug/Important Bio-Agent (IBA)

44	DNA (Deoxyribonucleic Acid)IBA 01/2023 - 11/2006
42	InflammasomesIBA 10/2023 - 08/2008
30	Proteins (Proteins, Gene)FDA Link 01/2023 - 01/2004
29	CytokinesIBA 01/2023 - 05/2009
25	InterferonsIBA 04/2024 - 09/2005
23	Interferon Type IIBA 11/2023 - 09/2005
17	Antiviral Agents (Antivirals)IBA 11/2023 - 07/2009
11	RNA (Ribonucleic Acid)IBA 02/2024 - 04/2007
11	Pattern Recognition ReceptorsIBA 01/2023 - 07/2006
10	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2023 - 07/2013
9	Nucleic AcidsIBA 11/2023 - 04/2007
9	Phosphotransferases (Kinase)IBA 01/2023 - 08/2011
8	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2018 - 01/2004
7	LigandsIBA 11/2023 - 08/2013
7	Interleukin-18 (Interleukin 18)IBA 05/2014 - 04/2010
6	Caspase 8 (Caspase-8)IBA 01/2023 - 11/2013
6	AutoantibodiesIBA 10/2022 - 02/2015
6	NucleotidesIBA 11/2015 - 07/2012
6	Interleukin-1 (Interleukin 1)IBA 02/2013 - 04/2010
5	Long Noncoding RNAIBA 02/2024 - 06/2016
5	InterleukinsIBA 12/2016 - 04/2010
4	Transcription Factors (Transcription Factor)IBA 02/2024 - 12/2002
4	LipopolysaccharidesIBA 01/2020 - 01/2004
4	Interferon Regulatory Factor-3 (Interferon Regulatory Factor 3)IBA 12/2017 - 05/2013
4	deoxyribonuclease II (DNASE II)IBA 02/2017 - 03/2013
4	Leucine (L-Leucine)FDA Link 09/2015 - 07/2012
3	Carrier Proteins (Binding Protein)IBA 11/2023 - 10/2013
3	LipidsIBA 09/2023 - 02/2009
3	Uric Acid (Urate)IBA 01/2020 - 08/2015
3	Peptides (Polypeptides)IBA 01/2020 - 08/2008
3	CaspasesIBA 01/2020 - 10/2005
3	Virulence Factors (Pathogenicity Factors)IBA 01/2018 - 10/2011
3	PyrinIBA 01/2016 - 03/2009
3	Adenosine Triphosphate (ATP)IBA 11/2015 - 03/2012
3	Tretinoin (Retinoic Acid)FDA LinkGeneric 09/2014 - 10/2005
3	RNA Helicases (RNA Helicase)IBA 01/2014 - 10/2005
3	VaccinesIBA 01/2014 - 08/2008
3	CholesterolIBA 08/2013 - 02/2009
3	ChemokinesIBA 08/2008 - 01/2004
3	Chemokine CCL5IBA 08/2008 - 01/2004
3	NF-kappa B (NF-kB)IBA 09/2005 - 12/2002
2	Interferon Regulatory FactorsIBA 02/2024 - 08/2014
2	Interleukin-12 (IL 12)IBA 02/2024 - 01/2022
2	itaconic acidIBA 01/2024 - 01/2018
2	N- alpha- benzoyl- N5- (2- chloro- 1- iminoethyl)- L- ornithine amideIBA 01/2023 - 01/2023
2	Adenosine Monophosphate (AMP)IBA 01/2023 - 01/2023
2	AntigensIBA 10/2022 - 03/2016
2	bis(3',5')-cyclic diguanylic acidIBA 01/2021 - 03/2014
2	Small Interfering RNA (siRNA)IBA 01/2021 - 08/2008
2	Nitric Oxide (Nitrogen Monoxide)FDA Link 01/2019 - 01/2013
2	Fas Ligand Protein (Fas Ligand)IBA 01/2018 - 09/2013
2	hemozoinIBA 01/2018 - 01/2014
2	Toll-Like Receptor 4IBA 12/2016 - 08/2012
2	EndotoxinsIBA 06/2016 - 08/2012
2	DNA VaccinesIBA 01/2016 - 01/2015
2	DNA receptor (receptor, DNA)IBA 01/2016 - 04/2012
2	Silicon Dioxide (Silica)FDA LinkGeneric 11/2015 - 08/2008
2	Poly I-CIBA 08/2015 - 09/2005
2	pristane (pristan)IBA 02/2015 - 09/2013
2	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2014 - 10/2013
2	vadimezanIBA 05/2013 - 11/2012
2	Interleukin-17 (Interleukin 17)IBA 07/2011 - 11/2010
2	Interleukin-1alpha (Interleukin 1 alpha)IBA 07/2009 - 11/2006
2	Double-Stranded RNA (RNA, Double Stranded)IBA 01/2004 - 05/2003
1	Biomarkers (Surrogate Marker)IBA 01/2024

Therapy/Procedure

11	Therapeutics 11/2023 - 04/2010
4	Immunotherapy 09/2023 - 11/2014
2	Oral Administration 01/2020 - 09/2010
2	Ligation 01/2018 - 07/2013